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[9] An increased proportion of pheomelanin is associated with lighter skin colour

These gut bacteria and their metabolites have an outsized impact by producing or stimulating different neurotransmitters (5HT, GABA) and metabolites (e.g

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Interestingly, sustained activation of ROS can trigger various forms of programmed cell death, including apoptosis, ferroptosis, pyroptosis, necroptosis, oxeiptosis, NETosis, parthanatos, autophagy, necrosis and immunogenic cell death [22, 213, 214] (Fig