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However, several zinc-related pathways may not properly respond to zinc repletion
18,19 While PDE-5 inhibitors have revolutionized the management of ED, the remainder of this review will focus on alternative treatment options and potential treatment strategies in the setting of failed PDE-5 inhibitor therapy or contraindications

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LMTM treatment in cellular models of PD resulted in a significant decrease in the formation of intracellular aggregates without any effect in terms of protein expression [286]
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