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Se, through GSH reductase and other selenoproteins, regulates the antioxidant activity in cells, thus protecting the human body against harmful effect of free radicals and, consequently, reducing the risk of cancer [47,48]

BCSCs have been shown to have a greater DNA damage repair capacity than NCSCs [229]

Activated innate immunity initiates the transcription of genes which lead to the production of signal molecules such as prostaglandins, pro-inflammatory cytokines, chemokines, and interleukins, and also activates the complement system, thus evoking the inflammatory cascade [16, 19]

Inferring tumour purity and stromal and immune cell admixture from expression data

At this point, we hypothesize that the individual training load via the training camp effect and the local altitude camp weather conditions probably influence nutritional recommendations to a greater extent than the potentially more mild hypoxic effects at lowmoderate altitudes

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