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In humans, it has been reported that LAL deficiency accounts for up to 3% of primary pediatric adrenal insufficiency 84,85
This was self-reported data by women in the US who had lipedema and underwent lipedema reduction surgery
doi: 10.3892/br.2018.1082
Am J Pathol 165:719728 Arner ES, Holmgren A (2000) Physiological functions of thioredoxin and thioredoxin reductase
