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The pharmacological activity of Ashwagandha is primarily attributed to a diverse range of bioactive constituents, among which withanolides constitute the most important class (90)

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Disease states can affect both of the physiologically related primary pharmacokinetic parameters: volume of distribution and clearance

These challenges limit peptides clinical application and explain the interest in alternative routes of peptide administration, particularly nose-to-brain (N-to-B) delivery, which allows protein and peptide drugs to reach the brain noninvasively

Effect of epitalon on interleukin-1beta signal transduction and the reaction of thymocyte blast transformation under stress