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Our results provide a possible mechanism in which upregulation of phosphorylated p53 and p16 maintain the cell cycle arrest of keloid fibroblasts, and FOXO4-DRI selectively induces apoptosis of keloid senescent fibroblasts by prompting p53-pS15 nuclear exclusion
Considerations for women with lupus Given that lupus disproportionately affects women, gender-specific peptide considerations matter

Fuks Z, Vlodavsky I, Andreeff M , McLoughlin M, Haimovitz-Friedman A

In MPTP-induced monkey model of PD, clioquinol significantly alleviated both dyskinesia and non-motor impairments, concomitant with a reduction in iron accumulation and ROS levels in the SN (228)
JNK is a subfamily of the canonical MAPK signal transduction pathway

Clin Cosmet Investig Dermatol
