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The HK4 isoform is more commonly referred to as glucokinase and it is encoded by the GCK gene

7) suggested that the GNCsiRNA complex can resist serum nucleases degradation of naked siRNA, prolong the circulation lifetime of siRNA in blood, enhance the accumulation of siRNA to tumours and knockdown the targeted NGF gene, thus inhibit the orthotopic pancreatic tumour progression

The senescence status is driven by UV- or hydrogen peroxide, while the protection of senescence is partially mediated by the inference of MMP-1 (Figure 5)

Inhibitors of NAD+ dependent histone deacetylases (sirtuins)

Biomarkers of diabetes-associated oxidative stress and antioxidant status in young diabetic patients with or without subclinical complications