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Furthermore, the salivary secretions, gastrointestinal mucosal secretions and factors of intra-luminal microflora jointly preserve the normal homeostasis (28, 29)

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When autophagy is activated, intracellular membrane vesicles form and engulf proteins, cytoplasm, organelles and protein aggregates, and these vesicles are then delivered to lysosomes where they and their contents are degraded

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