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CD patients have been found to have also alterations in adherence junction protein expression

Ohye C, Higuchi Y, Shibazaki T, et al

Additionally, estrogen-stimulated cyclooxygenase-2 (COX-2) activity drives prostaglandin E2 (PGE2) synthesis, creating a positive feedback loop that enhances local estrogen production and inflammation, further facilitating ectopic implantation ( 2.2 Immune system dysfunction and chronic inflammation Immune system dysfunction and chronic inflammation are central pathological features underlying endometriosis-associated infertility, characterized by aberrant immune cell activation, cytokine dysregulation, and impaired immune surveillance

McCullough, C

utilized MALDI to characterize the specific noncovalent complexes between guanidine derivatives and single-stranded DNA, using ATT as a matrix in the presence of DHC in positive ion mode and verifying the ability of ATT to characterize the noncovalent interactions between guanidine probes and ssDNA

Likewise, Lorent et al