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Fluctuations in temperature or exposure to light can reduce its bacteriostatic properties, shortening the usable life of the product

Furthermore, antibiotic-induced dysbiosis in adult mice with an established ENS triggers apoptosis of enteric neurons (108), although the precise cellular targets mediating this process remain unidentified

Following the success and approval of tirzepatide (Mounjaro, Eli Lilly, Indianapolis, IN, USA) in 2022 by FDA for treatment of T2DM, the SURMOUNT programme investigated its use as an anti-obesity medication in those without diabetes

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