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Cyclin-dependent kinase inhibitor 2B mediates excitotoxicity-induced death of retinal ganglion cells

However, there is a lack of human studies to investigate the anti-obesity effects of shiitake mushrooms

[88] involving 84 children with congenital hypothyroidism (CH) demonstrated the importance of sufficient copper levels for thyroid function and growth

In general, essential fatty acid deficiency (i.e., deficiency of both ALA and LA) has been observed only in patients with chronic fat malabsorption, cystic fibrosis, or those on parenteral nutrition without PUFA (86, 95) (see the article on Essential Fatty Acids)

For example, omega-3 fatty acids significantly decreased cardiovascular events in high-risk patients with hypertriglyceridemia, according to a double-blind, placebo-controlled research (72)

Through this action, omega-3 indirectly inhibits multiple pro-cancer signaling pathways, including the EGFR-mediated RAS/MAPK cascade and the PI3K/Akt survival pathway (59)