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It aids in the production of neurotransmitters, supporting memory, focus, concentration and overall cognitive performance, including your resilience to stress

The key point: the best option depends on the reason for low B12 and your clinical context

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Besides those with early diagnosis (ie, rapid disease progression), a similar trend towards poor prognosis regarding time to primary events (or survival) was found in the other two subgroups: being male and having %FVC 50 mg) for dose finding, and it is possible that these mega-doses might have even better outcome

For maintenance, a patch may help