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doi: 10.1074/mcp.M400221-MCP200 216 WalshAJCookRSManningHCHicksDJLafontantAArteagaCLet al

Grading of Recommendations Assessment, Development and Evaluation (GRADE)] (82)

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Nature and Nurture: What Determines Tumor Metabolic Phenotypes

To systematically investigate the functional consequences of antioxidant treatment in human HCC cells, a panel of HCC cell lines, including MHCC-97L, PLC/PRF/5, Hep3B and HepG2, were challenged with NAC and GSH followed by various assays to measure their functional changes

None of these mutants (excepted grxC3 and grxC4 ) had a perturbed hypocotyl elongation phenotype, suggesting that most of these candidates are not involved in the glutathione deficient mutants phenotype ( Figure 5D )