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Further mechanistic studies have found that terpenoids isolated from Chinese jujube kernel oil can significantly increase serotonin levels, promote GABA synthesis and GABA A receptor expression, inhibit the overexpression of Glu and NE, and simultaneously downregulate IL-1 levels and upregulate the activity of SOD and inducible nitric oxide synthase, thereby regulating neurotransmitters and inflammatory responses from multiple targets, thereby improving mood (Sun et al., 2024)

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The 2025 Hemophilia Treatment Centre Twinning (HTC) Program Twins of the Year are the Instituto Hematolgico Peditrico Dra Victria do Esprito Santo, Luanda, Angola and the IHTC Campinas, Hemocentro UNICAMP, University of Campinas (Brazil)

Key measurements include lipid peroxidation markers such as malondialdehyde and 4-hydroxynonenal, antioxidant defense markers such as GPX4 activity and the GSH/oxidized GSH ratio and advanced MRI-based assessments such as quantitative susceptibility mapping to quantify brain iron deposition (95,96)

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