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Gibbons, D., Morrissey, C

The data, together with the data from the same study measuring pyruvate levels described above, indicate that fasting increased the fumarate/pyruvate, and so also likely increased the malate/pyruvate, indicative of the [NADPH]/[NADP + ], in the spinal cord and several brain regions, including the hippocampus, brainstem, olfactory bulb, and potentially to a smaller extent in the cortex, while potentially decreasing in the hypothalamus (Shao et al., 2023)

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That is an advisory-committee proposal, not a final determination, and BPC-157 was never FDA-approved

doi: 10.1155/2015/725370.725370 [DOI] [PMC free article] [PubMed] [Google Scholar] 27.Vilhardt F., Haslund-Vinding J., Jaquet V., McBean G

Molecular insights of nanozymes from design to catalytic mechanism