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The altered pathways facilitate the production of SAM and maintain a high SAM/SAH ratio, which enhances H3K36me3 chromatin occupancy in Il1b gene and promotes the production of IL-1 (34)

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3-PLG-ibu-A-GSH) nanocarriers (yellow) and Golgi apparatus (magenta) in brain endothelial cells

Accumulating in the brain over years of exposure and causing severe damage to the surrounding brain cells
