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ZR2023QB267, ZR2024MB147, ZR2022QH291), the Taishan Scholars Program of Shandong Province (tsqnz20230622), and Joint Innovation Team for Clinical & Basic Research (202409), Jinan Science and technology plan (202134064)
In mice with global inactivation of the IGF-I gene, the proportionally reduced kidney size associates with reduced glomerular size and decreased numbers of nephrons [362]
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IGF-1 DES: The deletion of the first three amino acids also reduces IGFBP binding, though the mechanism differs from LR3
