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496,498 While -synuclein aggregates in the substantia nigra provide the most compelling link to the diseases motor manifestations, they first develop in other brain regions (e.g., the olfactory bulb) and gradually develop more extensively throughout the brain
P., Meinsma R., and van Gennip A
SCFAs also activate G-protein-coupled receptors (GPCRs) and modulate histone acetylation, thereby influencing immune tolerance [96]
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