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SIRT1 exhibits diverse subcellular localizations, being found in the nucleus, cytoplasm, or both, depending on the cell type (Sgadari et al., 2023)

REST can be activated by a variety of stressors, including oxidative stress, DNA damage, and amyloid beta, reflecting the brains adaptive mechanisms (Lu et al., 2014)

doi: 10.1186/1471-2431-3-9

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Metabolically flexible people efficiently switch between burning carbohydrates and fats