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The combination arm was terminated early due to severe adverse events and deaths, while NAC alone showed no significant effect on lung function, though secondary endpoints (6MWD, QoL) improved modestly (139)

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Sherman BT, Hao M, Qiu J, Jiao X, Baseler MW, Lane HC, et al

To mimic the transportation route of an orally administered drug via the sinusoidal blood flow, the drug compounds were perfused through the vascular cultivation chamber

doi: 10.1038/nrendo.2016.205 70 DongTZhiLBhayanaBWuMX
