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It should be noted that in the AVIATOR trial that evaluated ritonavir-boosted paritaprevir, ombitasvir and dasabuvir, the C316N RAS at baseline had no significant impact on treatment outcome 87

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The positive immunohistochemical reaction with the anti-melanosomal antigen HMB45 was detected (Figure 3g), low proliferative activity in most of the tumor, amounting to 1% according to the proliferative activity index Ki67

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There were no psammoma bodies

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