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Decreased HHIP expression relieves inhibition of PKM2, accelerating glycolysis and lactate production to promote cell proliferation ( 4.3.2 Key cytokines and signaling pathways IL-4 and IL-13 are secreted by Th2 cells and mast cells, activating the STAT6 pathway to promote ASMC proliferation and goblet cell mucus secretion, while upregulating PTGES expression to initiate the PTGES-AKT-HIF-1 pathway

J.ShimodaK.et al (2017)

The effect of diabetes mellitus on apoptosis in hippocampus: Cellular and molecular aspects