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Clinical evidence pertaining to migraines, oxidative stress, and neurogenic inflammation, along with experimental evidence of topiramates antioxidative and anti-inflammatory effects, provide strong hypothetical support for the idea that topiramate may treat migraines by blocking oxidative stress and neurogenic inflammation pathways

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By providing clear explanations of how different factors influence dosing, patients can become more engaged in their treatment plans

FIGURE 1 FIGURE 2 FIGURE 3 TABLE 1 Parameter estimates of the final model and 95% confidential interval

Vujic, G., Jajac Knez, A., Despot Stefanovic, V

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