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Description
When the API is absorbed, it first reaches the hepatic portal vein, and is then transported to the liver

PMID: 89 MoertelCLXiaJLaRueRWaldronNNAndersenBMPrinsRMet al
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CADASIL accelerated by acute hypotension: Arterial and venous contribution to leukoaraiosis

Research applications

For patients with severe hepatic impairment (Child-Pugh Class C) , Esomeprazole metabolism is significantly reduced and plasma concentrations are substantially elevated
