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In an open-label clinical trial involving patients with severe COVID-19, the use of Tranilast, a potential NLRP3 inflammasome inhibitor, was found to decrease the neutrophil-to-lymphocyte ratio (NLR) and levels of IL-1 and TNF- [71]

[DOI] [PubMed] [Google Scholar] Fichman Y, Mittler R

10.1016/j.redox.2022.102475 Redox Biol

Research progress on ferroptosis in diabetic kidney disease

Association of T and NK Cell Phenotype with the Diagnosis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Front
