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Further studies tell us that both injection and intranasal administration of DSIP effectively pass the blood brain barrier, significantly increasing the cortical delta activity (delta waves)

Subcutaneous injections offer a more accessible self-administered alternative but still require needles, sterile preparation, and proper storage

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2.1 Subtypes and localization in the nervous system There are two main classes of glutamate transporters: EAATs, which are dependent on an electrochemical gradient of sodium (Na + ) ions, and the vesicular glutamate transporters (VGLUT-1-3) and cystine-glutamate antiporters (xCT), which are Na + -independent (Table 1)