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The Bcl-2 family of proteins and mitochondrial outer membrane Permeabilisation

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For instance, glutamine helps maintain the integrity of the intestinal mucosa, which is crucial for preventing infections and ensuring efficient nutrient absorption

YM1, a protein with high sequence similarity to YM2, is considered an M2 macrophage marker in mice [87]

10.1016/j.jnutbio.2013.05.007 70 JiaZ.YangF.LiuX.ZhangX.HuW.ShengZ

Taken together, the present study provides evidence that GYY4137 functions as a cellular redox regulator to persulfidates the Cys 38 of NF-kB subunit p65 that effectively inhibits synovial macrophage pyroptosis by scavenging mitochondria oxidative stress in OA progression