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The readers of these phosphorylated histone marks primarily consist of 14-3-3 proteins and BRCT domain-containing proteins, which recognize and respond to the phosphorylation status of histones, further modulating cellular signaling and transcriptional regulation

GHK-Cu also influences the ubiquitin-proteasome system (UPS), upregulating dozens of genes involved in protein degradation and cellular maintenance, thereby supporting proteostasis under stress conditions (Pickart and Margolina 2018)

Selenium, a vital trace element known for its antioxidant properties (233), has attracted interest in schizophrenia research due to the observed abnormalities in its levels among patients (234,235)

D., Vaccaro A.R.., Przybylski, G.J

Treatment with D3T and ACDT upregulated Nrf2-mediated expression of ferritin and FPN1, while also protecting U-87MG cells from iron overload-induced cytotoxicity (Kulkarni et al., 2023)