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From the datamining sources through network biology conducted by Cytoscape, it was found that ACADM, CROT, CRAT, and ACADS are the most prominent genes involved in the function of LC and in the pathology of kidney disease

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In addition, TKTL1 lacks two vital histidine residues that are required for the catalytic processes and there is a substitution of a tryprophan at residue 124 for a serine (W124S)

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