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Special Population Studies Geographic & Ethnic Diversity Studies Asian Population Studies: Sub-analysis of Phase 2/3 trials in East Asian populations demonstrated consistent efficacy with cagrilintide monotherapy and CagriSema combination, with weight loss percentages comparable to or exceeding those in Western populations despite lower baseline BMI

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The population-averaged curve has a threshold (black dot) at glucose = 7.4 mmol/L and GSH approximately 462