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It remains a research compound that some clinics and individuals have begun using despite the lack of regulatory approval

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Pain Animal studies have shown beneficial effects of B12 on the regeneration of nerves and the inhibition of pain-signalling pathways, including cyclooxygenase enzymes

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Furthermore, the question whether Vit B12 should be considered as symptomatic treatment in PD or as a disease modifying therapy remains triggering and unresolved

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