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In 2009, one study using FDG-PET found that PD patients had significantly higher normalized brain metabolic rates of glucose in the bilateral globus pallidus and SN, contralateral caudate nucleus, and ipsilateral putamen relative to the clinically most affected body side, compared to healthy subjects [35]

Neurochem Res 37:469479 Chtourou Y et al (2010) Silymarin, a natural antioxidant, protects cerebral cortex against manganese-induced neurotoxicity in adult rats
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