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In short, it can reduce fine lines, wrinkles and improve skin texture significantly (and at crazy low concentrations, the studies were done with just 3 ppm that is 0.0003%)

Mishanina TV, Libiad M, Banerjee R

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Simply the use of bicarbonate perfusions leads to a selective increase of intratumoral pH concomitantly with a decrease of new metastases generation, as well as a remarkable improvement of the therapeutic efficiency of Doxorubicin in mouse models [115]

2016;2(5) doi: 10.20455/ros.2016.861

10.1002/biot.202200607