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In addition, since mitochondrial dysfunction leads to the activation of apoptosis, SIRT1 can directly regulate the apoptotic process by modulating acetylation of PGC-1 (Zhang et al., 2019)

Intrinsic apoptosis pathway is activated by ISA in many reports (Lu et al., 2018

10.1097/FJC.0b013e3182239eb7 297 YamaguchiT.SanoK.TakakuraK.SaitoI.ShinoharaY.AsanoT.et al (1998)

The solid tissues of the immune system also need C for optimal function
Lerer L, Varia J (2022) A long trip into the universe: psychedelics and space travel

ROXY1, a member of the plant glutaredoxin family, is required for petal development in Arabidopsis thaliana
