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453 The initially discovered sirtuin agonists mainly upregulate target enzyme activity through allosteric effects and are classified into two primary categories based on their origins

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Glutathione is a naturally occurring antioxidant that is produced by our bodies to help protect our cells from damage caused by free radicals, which are unstable molecules that can harm our cells

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Chelated metals have significantly reduced catalytic activity to decompose hydrogen peroxide and form hydroxyl radicals (Fenton reaction)

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