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453 The initially discovered sirtuin agonists mainly upregulate target enzyme activity through allosteric effects and are classified into two primary categories based on their origins

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Glutathione is a naturally occurring antioxidant that is produced by our bodies to help protect our cells from damage caused by free radicals, which are unstable molecules that can harm our cells

Chelated metals have significantly reduced catalytic activity to decompose hydrogen peroxide and form hydroxyl radicals (Fenton reaction)
