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report says"
These mutations impair the bodys DNA repair process, leading to microsatellite instability and a dramatically elevated cancer risk: up to 50-80% lifetime risk for colorectal cancer (often early-onset, before age 50) and 40-60% for endometrial cancer, alongside increased dangers for ovarian, gastric, pancreatic, urinary tract, and other malignancies
A more predictive humanized model of endocrine disease
O., Matsukawa, T
The cardioprotection of the insulin-mediated PI3K/Akt/mTOR signaling pathway
[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Fomenko DE, Xing W, Adair BM, Thomas DJ, Gladyshev VN
