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The compound belongs to a class of heterocyclic quinolinium derivatives investigated for their interaction with biochemical regulatory enzymes and metabolic signalling systems

BPC 157 upregulates VEGFR2 expression in rats with hind limb ischemia and in endothelial cell culture

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However, FOXO4-DRI treatment significantly reduced the expression of these detrimental SASP factors and, critically, restored the proliferation of GC-1 spg cells in the co-culture system, as evidenced by CCK-8 assays and PCNA expression, without inducing apoptosis in the spermatogonia