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doi: 10.1073/pnas.0701078104
They have demonstrated potent inhibitory effects on the lipid peroxidation process in various cell models and animal disease models, including OA (Xu W

Psychiatry 80 , 730736 (2009)

10.4049/jimmunol.180.11.7664 [DOI] [PMC free article] [PubMed] [Google Scholar] Shinde A

OCTN1 ( SLC22A4 ), the first member of the OCTN subfamily, is widely expressed in various tissues, including bone marrow, heart, kidney, liver, intestine, muscle, placenta, and the nervous system [167]

Hence, both of these molecules demonstrated a strong neuroprotective impact and a propensity to promote neurite outgrowth, but no evidence of a synergistic effect was seen (Shanan et al., 2019)
