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W., Carroll V., OMay C., Champion A., Kirov S

Conversely, the complete absence of ApoE expression in AD mouse models (APP/PS1 mice) containing both APP and PS1 mutations enhances A deposition and overall plaque size (Ulrich et al., 2018)

Vu NT, Kim M, Stephenson DJ, MacKnight HP, Chalfant CE

Biochem Biophys Res Commun 506(3):557562 Ghatak S, Hascall VC, Markwald RR, Feghali-Bostwick C, Artlett CM, Gooz M, Bogatkevich GS, Atanelishvili I, Silver RM, Wood J (2017) Transforming growth factor 1 (TGF1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis

The PI3K/Akt pathway, as a core anti-apoptotic regulatory axis, plays a key role in maintaining the integrity of the intestinal barrier by regulating effector molecules, such as Bcl-2 family proteins and caspase-3 ( Citrus unshiu peel (Chen pi) water extract (CUP) upregulated the expression of anti-apoptotic proteins Bcl-2 and Survivin by significantly inhibiting the expression of pro-apoptotic proteins Bax and caspase-3 in colonic tissues