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In life-threatening cases, 5,000,000mcg of B12 is given directly to the veins within a 15 minute window
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However, oral supplements are appropriate for many individuals

But if your B12 is high without supplementation , it can be a marker for underlying conditions that require medical evaluation, including liver disease, kidney dysfunction, and certain cancers

Molecular Nutrition and Food Research

Are recovering from surgery: A bariatric procedure, such as gastric bypass for weight loss, can reduce the amount of stomach acid necessary for B12 absorption
