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This sustained activation amplifies cytokine production and exacerbates oxidative stress damage [15]

doi: 10.1038/mp.2016.80 83 ChenJDongBFengXJiangDChenGLongCet al

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Reduction or reversal of fibrosis is actively being investigated to ameliorate symptoms of DMD

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The CUR-MM-ISGs, optimized using central composite design-response surface methodology, prolonged the ocular surface residence time and enhanced corneal permeability, leading to increased CUR bioavailability, reduced clearance and improved bioactivity