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Description
More recently, a multiple hits theory has been proposed, with the addition of other pathogenic factors in NAFLD development: low-grade chronic inflammation, genetic and epigenetic mutations, and intestinal microbiota

Results Eleven proteins had statistically significant associations with fasting C-peptide/glucose

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In contrast, CHOP, which is itself transcriptionally upregulated by ATF4, acts as a negative feedback regulator
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Fast forward to today there are now a fair few