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Ionic liquid matrix-based dispersive liquid-liquid microextraction for enhanced MALDI-MS analysis of phospholipids in soybean

By systematically elucidating ionization mechanisms, accelerating the development of high-performance matrices with the help of AI, optimizing matrix crystallization processes, and establishing standardized databases and sharing platforms, MALDI technology is expected to undergo breakthroughs in quantitative accuracy, spatial resolution, and multi-omics applicability