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As a Phase 1 trial, the research focuses on understanding how the treatment works in people, offering participants the chance to be among the first to receive this potential new therapy

Diabetes 62 , 29682977 (2013)

[DOI] [PMC free article] [PubMed] 60.Carboni JM, Wittman M, Yang Z, Lee F, Greer A, Hurlburt W, et al

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This mechanistic debate has been addressed in subsequent literature as reflecting differences in cell culture conditions, peptide batches, and choice of IGF-1 axis inhibitors and does not invalidate the substantial positive evidence base but represents an important research context requiring careful experimental design

Biochemistry 5 AntonioniA.FantiniC.DimauroI.CaporossiD