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Rifampicin and isoniazid The combination of rifampicin and isoniazid is used to treat tuberculosis

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On the other hand, eHSP can also function as a stress signalling and pro-inflammatory molecule by interacting with Toll-like receptors 2 (TLR2) and 4 (TLR4) [164]

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Superoxide can also combine with nitric oxide to generate peroxynitrite (ONOO ) which rapidly oxidizes biological macromolecules (Beckman and Koppenol, 2 and the disassembly of Fe-S clusters can disable nutrient oxidation and ATP production which has been implicated in the pathogenesis of non-alcoholic fatty liver disease, obesity, diabetes mellitus, and several neurological disorders (James et al., 2012)