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Brand names like Ozempic, Rybelsus, and Wegovy underscore its role in improving health outcomes

There is no high-quality evidence documenting menstrual cycle alterations as a recognized adverse effect of semaglutide (Wegovy)

Inhibitors of DPP-4 participate in the pancreatic-endocrine-osseous axis by increasing endogenous GLP-1

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With antiamyloid antibodies Leqembi (lecanemab) and Kisunla (donanemab) now FDAapproved for early Alzheimers, attention is turning to combination strategies that address multiple disease pathways