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Adequate animal reproduction studies have not been conducted with atropine

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Collagen is the most abundant protein in the body, integral to the structure of skin, hair, nails, and connective tissues

[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Russell MW, du Manoir S, Collins FS, Brody LC

This tissue selectivity for COX inhibition explains the contrasting adverse effects produced by classical NSAIDs, including gastric ulceration and alterations in hemostasis which are not seen with either short- or long-term therapeutic use of APAP

Associated toxicity includes potential headaches and bleeding problems