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Nutrients 2021;14:67

In axial spondyloarthritis, patients with chronically elevated CRP also had increased metabolic comorbidities and atherosclerotic plaque.[ref] It is also theorized that higher CRP levels may affect fat cells and increase weight.[ref] For type 2 diabetes, researchers found that variants linked to an increase in CRP are also linked to an increased risk of diabetes.[ref] But other studies show that genetically higher CRP levels may not always cause diseases associated with chronic inflammation

Foxo3a governs early microglial proliferation and employs mitochondrial depolarization with caspase 3, 8, and 9 cleavage during oxidant induced apoptosis

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[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Dekker H, Schulten EAJM, Lichters I, van Ruijven L, van Essen HW, Blom G-J, Bloemena E, Ten Bruggenkate CM, Kullaa AM, Bravenboer N
