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In a study on lung cancer, targeting the ROS/Nrf2 axis with Nrf2 siRNA or Tangeretin was shown to suppress Nrf2, overcome MDR (downregulating P-gp), and synergize with Paclitaxel and AZD9291 in A549/T xenografts

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In the current study, the response in the liver cells was expected

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The TUNEL-positive cells with green fluorescence were detected under a fluorescent microscope (Leica DM6000B)

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Task Force Members: Tammie C

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Synthesis of Cr(IV)-GSH, Its identification and its free hydroxyl radical generation: A model compound for Cr(VI) carcinogenicity

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[DOI] [PubMed] [Google Scholar] 45.Fasciglione G.F., Marini S., DAlessio S., Politi V., Coletta M

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