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Description
In a study on lung cancer, targeting the ROS/Nrf2 axis with Nrf2 siRNA or Tangeretin was shown to suppress Nrf2, overcome MDR (downregulating P-gp), and synergize with Paclitaxel and AZD9291 in A549/T xenografts

In the current study, the response in the liver cells was expected

The TUNEL-positive cells with green fluorescence were detected under a fluorescent microscope (Leica DM6000B)

Task Force Members: Tammie C

Synthesis of Cr(IV)-GSH, Its identification and its free hydroxyl radical generation: A model compound for Cr(VI) carcinogenicity

[DOI] [PubMed] [Google Scholar] 45.Fasciglione G.F., Marini S., DAlessio S., Politi V., Coletta M