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Patients with specific genetic profiles may experience faster or slower dose tolerance, which directly impacts their optimal hydration timeline

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Different agents can feel different in practice: Some may produce stronger appetite suppression Some may be easier to tolerate during titration Some may support better adherence because the weekly routine feels simpler Some may have stronger overall weight loss, but at the cost of more GI friction The point is not to crown a universal winner

These effects usually improve over time as your body adjusts to the medication or the new dose

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The Rome IV diagnostic criteria are currently used to diagnose IBS, which is divided into four subgroups based on bowel habits, bowel function, and stool consistency: constipation dominant (IBS-C), diarrhea dominant (IBS-D), mixed (IBS-M), and unclassified/unspecified IBS (IBS-U) (10)